Difference between revisions of "Proposals"
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+ | |title=Proposals | ||
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+ | |description=Proposals: List of the projects | ||
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List of the projects | List of the projects | ||
+ | * '''Brain-computer interface with Functional data analysis''' Human behavioral analysis and forecasting requires models, that have to predict target variables of complex structure. We develop PLS and CCA (Projection to latent space and Canonic correlation analysis) methods towards the Multiview with continuous-time data representation. [[Projects/BCI-FDA: Brain-computer interface with Functional data analysis]] | ||
− | * '''MASSIV: Alternative splicing-inspired protein development''' Eukaryotes have evolved | + | * '''MASSIV: Alternative splicing-inspired protein development''' Eukaryotes have evolved transcription machinery that can augment the protein repertoire without increasing the genome size. The challenge here will be to design an artificial system able to learn the underlying rules of (functional) AS and to generalize to any protein sequence. [[Projects/MASSIV: Alternative splicing-inspired protein development|see details.]] |
− | * '''READY-GO: Prediction of protein functional from peptide sequences''' We propose to develop a probabilistic model able to identify such signals and guide the discovery of novel regulatory mechanisms associated | + | * '''READY-GO: Prediction of protein functional from peptide sequences''' We propose to develop a probabilistic model able to identify such signals and guide the discovery of novel regulatory mechanisms associated with them. The model should be interpretable. [[Projects/READY-GO: Prediction of protein functional from peptide sequences| see details.]] |
* '''CASF: Comparative assessment of scoring functions for docking problem''' | * '''CASF: Comparative assessment of scoring functions for docking problem''' | ||
− | Pharmacological research is concentrated on constructing a molecule, a ligand, which docks a given protein. This research is expensive since it goes in | + | Pharmacological research is concentrated on constructing a molecule, a ligand, which docks a given protein. This research is expensive since it goes in vitro. We have to propose a deep neural net to forecast the probability of docking, [[Projects/CASF: Comparative assessment of scoring functions|see details.]] |
* '''3D-image reconstruction for the lens-free microscopy''' | * '''3D-image reconstruction for the lens-free microscopy''' | ||
− | One has to reconstruct an image of a small biological object (of hundreds micrometers, like a eucaryotic cell). Its video comes from a device of a brand-new technology: | + | One has to reconstruct an image of a small biological object (of hundreds of micrometers, like a eucaryotic cell). Its video comes from a device of a brand-new technology: free lens microscopy. This project combines modeling of interference images and its Fourier transform and GANs, the generative and discriminative deep learning models [[Projects/FLM: Lens-free microscopy image reconstruction|see details.]] |
* '''Atom-resolution synchrotron image reconstruction''' | * '''Atom-resolution synchrotron image reconstruction''' | ||
− | For a given synchrotron image one has to reconstruct an object of nano-meter size. There given a [https://en.wikipedia.org/wiki/Reciprocal_lattice reciprocal lattice] image. We have to train a neural net to reconstruct the real and the complex part of a sample object, [[Projects/SRF: | + | For a given synchrotron image one has to reconstruct an object of nano-meter size. There given a [https://en.wikipedia.org/wiki/Reciprocal_lattice reciprocal lattice] image. We have to train a neural net to reconstruct the real and the complex part of a sample object, [[Projects/SRF: Synchrotron radiation facility deep image retrieval|see details.]] |
* '''Long-live health monitoring with wearable devices''' | * '''Long-live health monitoring with wearable devices''' | ||
− | For daily accelerometer and gyroscope time series we have to reconstruct typical hand movements and represent these movements as clusters in the phase space. | + | For daily accelerometer and gyroscope time series, we have to reconstruct typical hand movements and represent these movements as clusters in the phase space. |
* '''Time series segmentation in low-dimensional space''' | * '''Time series segmentation in low-dimensional space''' | ||
− | One has to mark | + | One has to mark up zero-phase segments of various hand movements using electronic watches. Neural nets on spherical harmonics seem to be a good tool. |
* '''Invariants and compositions of physical activities''' | * '''Invariants and compositions of physical activities''' | ||
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* '''Generating WANN: weighted agnostic neural networks''' | * '''Generating WANN: weighted agnostic neural networks''' | ||
− | We have to generate agnostic nets and ensembles of agnostic nets to solve one of the well-known reinforcement learning problems: controlling toy cars on the road, steps, | + | We have to generate agnostic nets and ensembles of agnostic nets to solve one of the well-known reinforcement learning problems: controlling toy cars on the road, steps, and pendulums. |
* '''GAN creates WANN: generative adversarial network generates agnostic networks''' | * '''GAN creates WANN: generative adversarial network generates agnostic networks''' | ||
We have to develop a variational autoencoder, VAE, to generate simple agnostic networks, which are evaluated by some discriminative model. | We have to develop a variational autoencoder, VAE, to generate simple agnostic networks, which are evaluated by some discriminative model. |
Latest revision as of 00:33, 17 February 2024
List of the projects
- Brain-computer interface with Functional data analysis Human behavioral analysis and forecasting requires models, that have to predict target variables of complex structure. We develop PLS and CCA (Projection to latent space and Canonic correlation analysis) methods towards the Multiview with continuous-time data representation. Projects/BCI-FDA: Brain-computer interface with Functional data analysis
- MASSIV: Alternative splicing-inspired protein development Eukaryotes have evolved transcription machinery that can augment the protein repertoire without increasing the genome size. The challenge here will be to design an artificial system able to learn the underlying rules of (functional) AS and to generalize to any protein sequence. see details.
- READY-GO: Prediction of protein functional from peptide sequences We propose to develop a probabilistic model able to identify such signals and guide the discovery of novel regulatory mechanisms associated with them. The model should be interpretable. see details.
- CASF: Comparative assessment of scoring functions for docking problem
Pharmacological research is concentrated on constructing a molecule, a ligand, which docks a given protein. This research is expensive since it goes in vitro. We have to propose a deep neural net to forecast the probability of docking, see details.
- 3D-image reconstruction for the lens-free microscopy
One has to reconstruct an image of a small biological object (of hundreds of micrometers, like a eucaryotic cell). Its video comes from a device of a brand-new technology: free lens microscopy. This project combines modeling of interference images and its Fourier transform and GANs, the generative and discriminative deep learning models see details.
- Atom-resolution synchrotron image reconstruction
For a given synchrotron image one has to reconstruct an object of nano-meter size. There given a reciprocal lattice image. We have to train a neural net to reconstruct the real and the complex part of a sample object, see details.
- Long-live health monitoring with wearable devices
For daily accelerometer and gyroscope time series, we have to reconstruct typical hand movements and represent these movements as clusters in the phase space.
- Time series segmentation in low-dimensional space
One has to mark up zero-phase segments of various hand movements using electronic watches. Neural nets on spherical harmonics seem to be a good tool.
- Invariants and compositions of physical activities
We have to create a model to describe simple hand movements and compositions of movements. The composition of physical models must fit the composition of machine learning models.
- Generating WANN: weighted agnostic neural networks
We have to generate agnostic nets and ensembles of agnostic nets to solve one of the well-known reinforcement learning problems: controlling toy cars on the road, steps, and pendulums.
- GAN creates WANN: generative adversarial network generates agnostic networks
We have to develop a variational autoencoder, VAE, to generate simple agnostic networks, which are evaluated by some discriminative model.